Adverse effects
Rarely gastrointestinal disorders
including nausea and diarrhoea, skin reactions and fever
have been reported.
In case of gastrointestinal disorders, the dosage should
be reduced or the treatment temporarily withdrawn.
In case of skin reactions and fever, the treatment must
be stopped and the treating physician informed as this
may constitute an allergic reaction.
Doxium
tablets contain sodium bisulfite as antioxidant which
may cause allergic reactions, nausea and diarrhea in predisposed
patients. These allergic reactions may lead to anaphylactic
shock and life-threatening asthma attacks. The prevalence
in the general population is not known, but is probably
low.
However, sulfite hypersensitivity is observed more frequently
in asthmatics than in non-asthmatics (see "Contraindications").
In case of hypersensitity reactions, the intake of Doxium
tablets must be stopped immediately. |
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